For Patients
323-986-5100Traumatic Brain Injury and Hormone Therapy
Trauma to the brain can often damage the hypothalamic-pituitary system and can severely impair normal hormonal function.
The SottoPelle® Bioidentical Hormone Replacement Method can assist those with Traumatic Brain Injury patients live a fuller life!
Visit the SottoPelle® Brain and Mental Health page for more information about how hormonal balance supports a healthy brain and offers protection for neurodegenerative conditions.
Happy, Healthy Brain
Estrogen, testosterone and progesterone transmit neural signals to the brain’s hormone receptors, triggering the release of hundreds of neurotransmitters including dopamine, serotonin, oxytocin and endorphins. Hormones influence our memory, movement, cognitive function, sleep and motivation, as well as our moods, emotions and overall mental health. Hormones also provide neuroprotection and can help patients with neurodegenerative conditions such as TBI, Parkinson’s, Alzheimer’s and dementia.
Graphic: Andrade Design, California/Andradedesign.com
Find a ProviderHow Hormones Impact The Well-Being
Of Traumatic Brain Injury Patients
“Heal Traumatic Brain Injury with Bioidentical Hormones”
Compiled by Michael Downey
As seen in Life Extension, Feb. 2015
Traumatic brain injury afflicts nearly 1.7 million Americans annually and causes devastating cognitive, emotional, and physical deficits.
Standard therapies frequently fail to provide significant recovery after the acute phase, and chronic symptoms can linger over a lifetime.
Innovative physicians are discovering that brain trauma can trigger deficiencies in certain hormones. When these hormones are restored using precise bioidentical therapy, a reversal of functional deficits associated with brain injury has been shown.
Beyond brain injuries, accumulating evidence suggests that—as rates of dementia and Alzheimer’s disease continue to explode—replenishing these hormones may help inhibit degenerative diseases.
… And just as Dr. Tutera has shown that TBI symptoms can be treated and possibly reversed with sex hormones, the same hormones have been shown to reduce the risk of neurodegenerative diseases.
“How Testosterone Helps Boost Your Biceps And Your Brain”
by Catherine J. Rourke
As seen in Maxim, Oct. 14, 2024
Testosterone fuels the brain, influencing the neurotransmitters regulating your memory, mood, motor control, behavior and cognitive functions. Research indicates it has been used to treat osteoporosis, metabolic syndrome and cholesterol. T therapy may help prevent Alzheimer’s and other neurodegenerative diseases.
As SottoPelle’s CEO, CarolAnn Tutera is the original female industry leader, continuing what she and Dr. Tutera started in the 1990s. “We’re working with ex-NFL players and veterans and excited about the progress they’re making,” she said. “We support everyone on their journey and have so many success stories.”
Advances in TRT therapy show it’s helping men stay sharp, strong and energized. A 2023 Harvard Health study cites the cardiovascular safety of TRT in preventing strokes and heart attacks. A recent meta-analysis of 35 clinical studies found TRT restored normal T levels to enhance men’s strength, brainpower and vitality without cardiovascular risks.
SottoPelle is committed to helping athletes, veterans, and anyone with head injuries or low T to regain their muscle and mojo.
“Boost Your Brain with Bioidentical Hormone Pellet Therapy”
by Catherine J. Rourke
As seen in Medical Daily, Nov. 13, 2025
Most people associate the sex hormones with puberty and reproduction. But estrogen, testosterone, and progesterone serve a much greater purpose in human health.
Numerous studies demonstrate how the sex hormones act like a master switch for every organ and tissue of the body, regulating cognitive function, mood, sleep, and all the neurotransmitters. In fact, brain health hinges completely on hormonal balance.
One visionary medical team already connected the dots over 30 years ago, pioneering a safe, effective method for body and brain health. CarolAnn Tutera, president and CEO of SottoPelle®/Tutera Medical®, co-founded the company with her late husband, Dr. Gino Tutera, a medical pioneer renowned for his groundbreaking innovations using bioidentical hormone pellets.
Backed by 87 years of scientific research and slipped under the skin, subcutaneous pellets demonstrate the greatest efficacy in penetrating the blood-brain barrier for consistent hormone distribution.
Testimonials
From Traumatic Brain Injury Patients
JIM MCMAHON
Former NFL Quarterback
“I have started the pellets and Dr. Tutera and his team are doing great things to help athletes like me.”
PAUL KRAUSE
Minnesota Vikings/Pro Football Hall of Famer
“SottoPelle® has really turned my life around. I am thinking much clearer, my memory is sharper, and my energy level is amazing!”
Why the SottoPelle® Hormone Method?
● Ranked The #1 Hormone Therapy Provider 8 Years in a Row!
● Thousands of Providers in hormone therapy since 1993
● Over 250,000 Happy Clients and Counting
● Hundreds of doctors
● 200+ five star google reviews
Find a Provider
Feeling great has
never been so easy.
You’re an original and unique. Our pellet therapy is tailored to each patient’s precise and individual needs. We use safe state of the art technology to provide you with personalized patient treatment and care. SottoPelle® helps you reconnect with the best you can be at any age.